health care  
 
Articles in skin symptoms, disorders, infections: Blackheads (comedones) Chemical burn Cyanosis Diaper rash Dry skin (xerosis) Epicanthal folds Frostbite treatment Intertrigo Itching Oily skin Petechiae and purpura Skin blushing\flushing Skin rashes Skin turgor Stretch marks Sunburn Swelling Pressure ulcer (bad Sores, decubitus ulcers) Wrinkles Acanthosis nigricans Age spots Bullous pemphigoid Eczema Ectodermal dysplasia Erythema multiforme Freckles Granuloma annulare Ichthyosis vulgaris Impetigo Lichen planus Lichen simplex chronicus Liver spots Pemphigus vulgaris Pityriasis rubra pilaris Pityriasis alba Pityriasis rosea Cellulitis Creeping eruption Cutaneous anthrax Cutaneous candidiasis Ecthyma Erysipelas Folliculitis Molluscum contagiosum Necrotizing fasciitis Perichondritis Paronychia Ringworm Scalded skin syndrome Scrofula Skin abscess Sporotrichosis

Skin blushing/flushing

Skin blushing or flushing is a sudden reddening of the face, neck and occasionally, upper chest. Flushing occurs because the blood vessels in the skin dilate. There are various causes. When flushing is produced by activity of the nerves to the blood vessels it is accompanied by sweating. Agents which act directly on the blood vessels cause dry flushing. Facial blushing is an involuntary reddening of the face due to embarrassment or stress. It is thought that facial blushing is caused by an overactive sympathetic nervous system. This system helps to regulate glands and organs without our conscious effort, and controls the diameter of blood vessels to the face. In some people, these nerves are unusually sensitive to emotional

stress. Given the right stimulus (such as embarrassment), the nerves prompt the blood vessels to open wide, flooding the skin with blood and causing the characteristic reddening of the face. In some people, the ears, neck and chest also blush. Severe facial blushing is common in people who have social phobia, an anxiety disorder in which the person experiences extreme and persistent anxiety in social and performance situations, and fears being judged, criticised, ridiculed or humiliated.

The function of cutaneous blood flow is nutrition of the skin and regulation of body heat. The higher the cutaneous blood flow, the more heat radiates. Restriction of cutaneous blood flow curtails the loss of body heat, which is important in a cold environment. The circulatory system of the skin contains three major types of blood vessels that enable it to fulfill these two important functions. The first type are arteries, capillaries, and veins that serve mainly nutrition needs. The second type is the subcutaneous venous plexus that plays a major role in the conduction of heat, and contains a major fraction of the cutaneous blood volume. The third type are arteriovenous anastomoses which can be found in areas of the body especially exposed to maximal cooling like the hands, feet, nose, lips and ears. These areas are called apical structures and are richly innervated. The anastomoses connect cutaneous arterioles and venules directly, playing an important role in the reduction of blood flow in a cold environment.

Blood flow in the cutaneous resistance vessels and the subcutaneous venous plexus are both neurally and locally regulated. However, there are some important differences. One is, that cutaneous resistance vessels exhibit a basal tone independently of innervation in reaction to passive stretch induced by blood pressure (Rowell. 1974). This intrinsic basal tone is normally absent in cutaneous capacitance vessels .

Along with this basal tone, all resistance vessels in the skin receive a tonic outflow from sympathetic vasoconstrictor fibers. This tonic outflow is inversely associated with body temperature. Vasodilation therefore occurs passively in resistance vessels the (alpha-adrenergic) vasoconstrictor tone decreases. Furthermore, an active neurogenic vasodilation must be assumed in the human skin. However, it is not clear if this vasodilation is mediated by specific vasodilator nerve fibers or if neuro-humoral effects are involved that are associated with the sympathetic cholinergic activation of sweat glands (Rowell. 1993; Lembeck & Holzbauer. 1988). Although some experiments lead to the conclusion that sympathetic outflow is involved in facial vasodilation (Drummond & Lance. 1987), 40 years of research have not clarified the mechanism behind active vasodilation.

Cutaneous veins also are richly innervated with sympathetic vasoconstrictor fibers. The effect of activation of the outflow of these fibers is reduced by local cooling. In addition, cutaneous veins are temporarily reactive to various other stimuli. Each of the following can cause remarkably intense venoconstriction without obvious value to the organism: emotional stimuli (e.g. startle, apprehension, discomfort), hyperventilation, deep inspiration, and the Valsalva maneuver (Rowell. 1974).

In resistance vessels, increased pressure mainly increases flow per time unit. In the cutaneous venous plexus with its generally slow flow rate, pressure mainly influences volume. Because of its enormous volume variability and its large potential capacity the venous plexus is believed to determine skin color (Rowell. 1993; Mellander, Andersson, Afzelius, & Hellstrand. 1982; Rowell. 1974). Since pronounced blushing is also characterized by a deep reddening of the skin, vasodilation of the venous plexus is probably the physical mechanism underlying it. But why is emotional blushing only visible or apparent in a specific area called the blush region? That area is restricted to the face, ears, neck, and in some rare cases the upper body. Two main hypotheses to explain this regional restriction have been proposed. One is that vasodilation takes place throughout the entire skin of the body but is only visible in the blush region due to special anatomical structure of that region. The second is that a specific form of vasodilation takes place exclusively in the blush region. It is likely, that a combination of these two factors accounts for blushing.

There is evidence that the blushing region is anatomically different in structure. The facial skin, for example, has more capillary loops per square millimeter and generally more vessels per unit volume than other skin areas. In addition, blood vessels of the cheek are wider in diameter, are nearer the surface, and visibility is less diminished by tissue fluid. Evidence for special vasodilation mechanisms was reported by Mellander and his colleagues (Mellander, Andersson, Afzelius, & Hellstrand. 1982). They studied buccal segments of the human facial veins in vitro. Unlike veins from other areas of the skin, facial veins responded with an active myogenic contraction to passive stretch and were therefore able to develop an intrinsic basal tone. Additionally Mellander et al. showed that the veins in this specific area were also supplied with beta-adrenoceptors in addition to the common alpha-adrenoceptors. These beta-adrenoceptors could exert a dilator mechanism on the above-described basal tone of the facial cutaneous venous plexus. Mellander and his colleagues propose that this mechanism is involved in emotional blushing. Drummond has partially confirmed this effect by pharmacological blocking experiments (Drummond. 1997). In a number of trials, he blocked both alpha-adrenergic receptors (with phentolamine) and beta-adrenergic receptors (with propranolol introduced transcutaneously by iontophoresis). Blushing was measured at the forehead using a dual channel laser Doppler flowmeter. Subjects were undergraduate students divided into frequent and infrequent blushers according to self-report. Their mean age was 22.9 years, which is especially favorable for assessing blushing, since young subjects are more likely to blush and blush more intensively. The subjects underwent several procedures, one of which was designed to produce blushing. Alpha-adrenergic blockade with phentolamine had no influence on the amount of blushing in frequent or in infrequent blushers, indicating that release of sympathetic vasoconstrictor tone does not substantially influence blushing. This result was expected since vasoconstrictor tone in the facial area is known to be generally low (van der Meer. 1985). Beta-adrenergic blockade with propranolol on the other hand decreased blushing in both frequent and infrequent blushers. However, despite complete blockade, blood flow still increased substantially during the embarrassment and blushing inducing procedure. Additional vasodilator mechanisms must therefore be involved. So far, no specific mechanism has been suggested.

Severe cases of blushing are known as idiopathic cranio-facial erythema. Just about any situation at all can bring on intense blushing (for example, the trigger can be as simple as casual conversation with friends) and it may take one or two minutes for the blush to disappear. Severe blushing can make it difficult for the person to feel comfortable in either social or professional situations. People who have social phobia are particularly prone to idiopathic cranio-facial erythema. Hyperhidrosis means excessive sweating. A person with hyperhidrosis can sweat heavily enough to soak their clothes. Once again, an overactive sympathetic nervous system is thought to be the cause, which explains why some people who have idiopathic cranio-facial erythema suffer from hyperhidrosis as well.

Skin care Mainpage

Recommended skin care products


ClearSkin Skin Wash
Natural skin wash with herbal ingredients for skin health and nourishment. A 100% natural, safe and proven herbal wash that cleanses skin thoroughly without drying or flaking.

Age-defense Active Day Cream
Age-defense active day cream contains ingredients specially chosen for their ability to reverse the visible signs of aging skin. Your skin will become softer, smoother and younger-looking!

Deep Active Cleansing Mask
Deep active cleansing mask is specially formulated for all skin types and gives your skin an extra deep cleansing treatment to remove toxins. Your skin will feel fresh and glowing.

Featured skin topics

Acne
Dermatitis
Psoriasis
Rosacea
Spider veins
Varicose veins
Vitiligo
Dry skin (xerosis)
Wrinkles
Age spots
Eczema
Freckles
Facial skin care
Dry skin care
Oily skin care
Skin whitening
Asian skin care
Black skin care
Organic skin care
Skin resurfacing
Face Lift
Dermabrasion
Skin care tips
Skin care recipes
Natural skin care


All information is intended for reference only. Please consult your physician for accurate medical advices and treatment. Copyright 2005, health-cares.net, all rights reserved. Last update: July 18, 2005