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Articles in skin conditions and diseases: Acne Actinic keratosis Albinism Basal cell nevus syndrome Bathing trunk nevus Birthmarks Cherry angioma Seborrheic keratosis Cutaneous skin tags Dermatitis Ehlers-Danlos syndrome Erythrasma Hives Ingrown toenails Keloid Keratosis pilaris Klippel-Trenaunay syndrome Leprosy Livedo reticularis Moles Mongolian blue spots Psoriasis Polymorphic light eruption Port wine stain Pyogenic granuloma Rosacea Scabies Scleroderma Sebaceous cysts Shingles Skin lesions Skin lesion of histoplasmosis Skin lesion of coccidioidomycosis Skin tags Smallpox Spider angioma Spider veins Superficial thrombophlebitis Tinea versicolor Urticaria pigmentosa Varicose veins Vitiligo Wegener's granulomatosis Xanthelasma and xanthoma

How is Wegener's granulomatosis diagnosed?

The diagnosis of Wegener's granulomatosis is confirmed by detecting both abnormal cellular formations, called granulomas, and vasculitis in a biopsy of tissue involved with the inflammatory process. For examples, an open lung biopsy or a kidney biopsy are commonly used in making a diagnosis of Wegener's granulomatosis. Wegener's granulomatosis

has symptoms similar to a number of other disorders, which may make it difficult to diagnose. However, for the most effective and successful treatment, early diagnosis is critical.

A doctor will ask about symptoms and perform a physical examination. Blood tests will be done. A blood test called ANCA helps diagnosis Wegener's granulomatosis. ANCA stands for Anti-Neutrophil Cytoplasmic Antibody, which is manufactured by the body's immune system. Since most people with Wegener's granulomatosis produce ANCA, they usually have a positive ANCA test, especially when the symptoms worsen.

A chest X-ray or chest CT (computed tomography) scan may be done to look for masses in the lungs. Urine studies may be performed to assess kidney function. The diagnosis often is confirmed by a biopsy (a small sample) of inflamed tissue and examination under a microscope. Usually, the biopsy is easy to get from inflamed areas in the nose or the skin, but sometimes a sample is needed from a lung or kidney.

More information on Wegener's granulomatosis

What is Wegener's granulomatosis? - Wegener's granulomatosis is an uncommon disorder characterized by inflammation of blood vessels (vasculitis).
What are symptoms of Wegener's granulomatosis? - Common symptoms and signs symptoms of Wegener's granulomatosis are pain in the sinuses and ears; nasal congestion and discharge and nosebleeds.
How is Wegener's granulomatosis diagnosed? - The diagnosis of Wegener's granulomatosis is confirmed by detecting both abnormal cellular formations and vasculitis.
What is the treatment for Wegener's granulomatosis? - Wegener's granulomatosis is often treated with a combination of corticosteroids and immunosuppressive drugs. 
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All information is intended for reference only. Please consult your physician for accurate medical advices and treatment. Copyright 2005,, all rights reserved. Last update: July 18, 2005